Plenary Lecture
Survey the Effect of Probiotic Doogh as a Bio-functional Medicine
Professor Khashayar Tabari
Young Researchers Club
Lahijan Branch
Islamic Azad University
Lahijan, Iran
E-mail: khashayar.tabari@yahoo.com
Abstract: At present, claims about reduction of disease risk are tentative and functional food as bio-functional medicine can be effective in this role. Among the most promising target is functional gastrointestinal disorder containing Irritable bowel syndrome (IBS) that is common through the world, including Iran, which is unclear and it has not been effective treatment. Therefore, it’s necessary to find a bio-functional medicine for treatment and control symptoms, including abdominal pain and defecation changes. This study was aimed to determine the effectiveness of probiotic doogh on the general relief of symptoms associated with IBS.
Methods: Subjects were recruited from volunteer groups of adolescent patients in Tehran. A total of sixty adolescent patients were randomized into two groups of trial and control. Pre- and post-treatment symptoms were investigated using a questionnaire. Thirty one patients received probiotic and 29 ones normal doogh for 3 weeks.
Probiotic doogh were manufactured by combination usual starters with Lactobacillus acidophilus LA5 and Bifidobacterium bifidum BB 12, and coded. The symptoms were followed before, during and after three weeks of treatment. Data were analyzed by SPSS (Ver. 17) and differences between groups were compared statistically using of chi-square and t-test.
Results: A total number of 60 patients were recruited in this study of whom 36 (60%) were female and 24(40%) male. The average age of participants was 16.1±9 which did not differ between two groups. The onset of symptoms did not show any difference between two groups. The trial group had a history of 3.7±3.1 years while this was 3.5±2.9 for the controls.
In overall, patients who were given probiotic doogh had shown a better response in the control of abdominal pain and flatulence than those who were treated with normal doogh. A significant difference was shown between two groups in the response of treatment for other symptoms including epigastric pain, vomiting, frequency of defecation and feces consistency.
Conclusion: According to our research, adding probiotic doogh to the diet may relieve symptoms of IBS especially, abdominal pain and flatulence and favorably influence on colonic flora. The most promising health benefits are reduction in symptoms of IBS and enhancement of the immune system.
Brief Biography of the Speaker: Professor of Science and Technology in Medicine Department, Payame Noor University, Iran. He is member in International Society of Biomedicals, member in International Society of Clinical Bioclinical and Biostatistics and also he is member of Young Researchers Club at Islamic Azad University.
His works concern the conception, synthesis and physicochemical studies of new biomaterials for applications in surgery, Biocompatibility and kinetic of bioactivity. He is also worked in many research project performed in Molecular Techniques Unit.
He is author of more than 20 articles published in international journals and 30 international conferences.