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Yumi Takizawa



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Yumi Takizawa


WSEAS Transactions on Biology and Biomedicine


Print ISSN: 1109-9518
E-ISSN: 2224-2902

Volume 15, 2018

Notice: As of 2014 and for the forthcoming years, the publication frequency/periodicity of WSEAS Journals is adapted to the 'continuously updated' model. What this means is that instead of being separated into issues, new papers will be added on a continuous basis, allowing a more regular flow and shorter publication times. The papers will appear in reverse order, therefore the most recent one will be on top.



Electrophysical Model and Analysis of Myelinated and Unmyelinated Axons in Neurons

AUTHORS: Yumi Takizawa

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ABSTRACT: This paper presents electrophysical model and analysis of myelinated and unmyelinated axon in neurons. Results of studies of characteristics of axon is described in this paper. The axon transmits electrical signals of pulse and plateau from the soma to output synapse for post neurons. Transmission loss and velocity are extremely low and faster in the axon with myelination and large diameter. The electro saltatory transmission model was said for lossless and high velocity transmission. By this model, almost all electrical energy are transmitted not inside but outside of the axon. It causes severe cross talk among axons. This paper first gives effective models and analysis for axons without myelination and small diameter. Based on the above, transmission characteristics with myelination and large diameter are solved in equations. It was found that (a) wider transmission bandwidth is realized by myelination and large diameter. (b) Na channels gathered between myelinations helps low loss transmission with increased positive ions.

KEYWORDS: Electrophysical modelling of axon, Myelination and unmyelination in axon, Velocity and bandwidth, Attenuation, Phase rotation, The electro saltatory transmission of the nerve impulse

REFERENCES:

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[3] Tasaki I., The electro saltatory transmission of the nerve impulse and the effect of narcosis upon the nerve fiber. Am. J. Physiol. 127: 211- 227, 1939.

[4] Gasser H.S., The Nobel Prize in Physiology or Medicine 1944, http://www.nobelprize.org/nobel_prizes/medici ne/laureates/1944/gasser-bio.html.

[5] Siegel A., Sapru H N., Essential Neuroscience, the third edition, p.257, 2014.

[6] Fukasawa A., Takizawa Y., Activity of a Neuron and Formulation of a Neural Group for Synchronization and Signal Processing, Proc. of the Int. Conf. on Neurology, pp.242-247, Kos, Greece, July 2012, The Best Paper Prize of NEUROLOGY’12 awarded by WSEAS/NAUN.

[7] Fukasawa A. Takizawa Y., Activity of a Neuron and Formulation of a Neural Group for Synchronized Systems, International Journal of Biology and Biomedical Engineering, Issue 2, vol. 6, pp. 149-156, 2012.

[8] Fukasawa A., Takizawa Y., Activity of a Neuron and Formulation of a Neural Group based on Mutual Injection in keeping with system synchronization, Proc. of International conference on Circuit, Systems, Control, Signals (CSCS’12), pp. 53 58, Barcelona, Spain, Oct. 17, 2012.

[9] Fukasawa A., Takizawa Y., Activities of Excitatory Cells of Neuron and Unicellular Organism, Proc. of International Conference on Health Science and Biomedical Systems (HSBS'14), pp.11-15, Nov., 2014.

[10] akizawa Y., Fukasawa A., Activities of Excitatory Cells of Neuron and Unicellular Organism, International Journal of Biology and Biomedical Engineering, vol.9, pp.98-103, 2015.

[11] Takizawa Y., Fukasawa A., Excitation of a Neuron for Characteristic Potential Generation, WSEAS Transactions on Biology and Biomedicine, vol. 12, pp.69-78, 2015.

[12] Takizawa Y., Fukasawa A., Formulation of Topographical Mapping in Brain with a Synchronous Neural System, Proceedings of the 15th International Conference on Mathematical Methods, Computational Techniques and Intelligent Systems (MAMECTIS’13), pp. 60 65, Lemesos, Cyprus, Mar. 21-23, 2013.

[13] Stetson D.S.; Albers J.W.; Silverstein B.A., Wolfe R.A., 'Effects of Age, Sex, and Anthropometric Factors on Nerve Conduction Measures', Muscle & Nerve 15, pp. 1095 1104, October 1992.

[14] Hodgkin A. L., Huxley A. F., A quantitative description of membrane current and its application to conduction and excitation in nerve, Journal of Physiology, vol. 117, pp. 500-544, 1952.

[15] Fukasawa A., Takizawa Y., Electrophysical Modelling and Analysis of Axon in Neurons, International Journal of Biology and Biomedicine, Volume 1, pp. 66-71, 2016

WSEAS Transactions on Biology and Biomedicine, ISSN / E-ISSN: 1109-9518 / 2224-2902, Volume 15, 2018, Art. #1, pp. 1-7


Copyright © 2018 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution License 4.0

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