AUTHORS: Yumi Takizawa

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ABSTRACT: This paper presents model and analysis of electrophysical activities in neurons corresponding to pulse and plateau potentials. When the inner (cytoplasm) potential grows up beyond zero potential (in the external liquid), positive ions cannot flow anymore into the cytoplasm. So effective knowledge of excitation was not provided by the conventional Hodgkin Huxley model. This paper first presents a model and analysis of a depletion layer formed at the boundary between positive and negative (p – n) zones. This paper then gives an advanced model of activity, which structure is composed of three zone separated by two junctions induced dynamically in cytoplasm for input stimulation. This paper then gives equivalent circuit of “activity” with input and surround passive circuit. This model are commonly applied to dual modes of excitation of positive and negative potential generations, and also applied to output signals with pulse and plateau for the first and the second messengers.

KEYWORDS: Neuron, Activity, Electrophysical model, Zone and depletion layer, Liquid junction, Positive / Negative potentials, Pulse and plateau

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