Other Articles by Author(s)

Mariusz Chmielewski
Michał Nowotarski

Author(s) and WSEAS

Mariusz Chmielewski
Michał Nowotarski

WSEAS Transactions on Biology and Biomedicine

Print ISSN: 1109-9518
E-ISSN: 2224-2902

Volume 14, 2017

Notice: As of 2014 and for the forthcoming years, the publication frequency/periodicity of WSEAS Journals is adapted to the 'continuously updated' model. What this means is that instead of being separated into issues, new papers will be added on a continuous basis, allowing a more regular flow and shorter publication times. The papers will appear in reverse order, therefore the most recent one will be on top.

The Method for Processing Electromyography and Inertial Sensors Supporting Chosen Set of Neurological Symptoms for Clinical Trials Support and Treatment Assessment

AUTHORS: Mariusz Chmielewski, Michał Nowotarski

Download as PDF

ABSTRACT: This paper discusses method and tool for supporting and assisting clinical trials of pharmaceutical drugs utilising wearables and mobile technologies. Biomedical sensors and handhelds deliver new opportunities to gather and process medical data. Presented method implements such observations and delivers new, convenient means for remote patient monitoring. Clinical trials require methodology and tools to support iterative, accurate assessment of drug intake and treatment effects. Currently available methods rely mostly on analogue approach (booklets) in which a trial participant is reporting symptoms in a booklet. Such approach often can be biased by unpunctual, not precise reporting. Handhelds can support trial processes by automatically scheduling and recording an actual time of reports and most of all it can record the inertial and biometric sensor data during the survey process. Presented analytical method (tremors recognition) and its software implementation offer consistent approach to clinical trials assistance transforming Android smartphone into remote reporting and notification tool. PatronDroid tool supplements also features for sensor based disease diagnostics identifying PD tremors as well as specific tonic or clonic phases. The tool’s feature composition delivers convenient and reliable utility which can assist patients and medical staff during the process objectifying the clinical tests, helping to ensure good quality of the clinical trial data, instantly available and easily accessible.

KEYWORDS: mobile applications, wearable sensors, telemedicine, clinical trials, neurological symptoms


[1] M. Nowotarski, Opracowanie algorytmów decyzyjnych wykorzystujących wybrane sygnały inercjalne oraz biomedyczne do identyfikacji zaburzeń neurologicznych oraz oprogramowania mobilnego na platformę Android, master’s thesis, M. Chmielewski (supervisor), MUT (2016),

[2] R. LeMoyne, Wearable and wireless accelerometer systems for monitoring Parkinson’s disease patients—A perspective review, Advances in Parkinson’s Disease, 2, 113-115 (2013)

[3] S.H. Roy, B.T. Cole, L.D. Gilmore, C.J. De Luca, C.A. Thomas, M.M. Saint-Hilaire, S.H. Nawab, High-Resolution Tracking of Motor Disorders in Parkinson’s Disease During Unconstrained Activity, Movement Disorders, 28, 1080-1087 (2013)

[4] S. Beniczky, T. Polster, T. W. Kjaer, H. Hjalgrim, Detection of generalized tonic–clonic seizures by a wireless wrist accelerometer: A prospective, multicenter study, Epilepsia, 54, 58-61 (2013)

[5] M.M. Velez, R.S. Fisher, V. Bartlett, S. Le, Tracking generalized tonic-clonic seizures with a wrist accelerometer linked to an online database, Seizure, 39, 13-18 (2016)

[6] J.R. Villar, M. Menendez, J. Sedano, E. de la Cal, V.M. Gonzalez, Analyzing accelerometer data for epilepsy episode recognition, 10th International Conference on Soft Computing Models in Industrial and Environmental Applications. Advances in Intelligent Systems and Computing, 368, 39-48, Springer, Cham (2015) -0.3 -0.2 -0.1 0 0.1 0.2 0.3 20:232 20:461 20:656 20:854 -18 -13 -8 -3 2 7 12 17 Tremor

[m/s 2 ] Time

[s] Voltage


[7] SENSE project Wiki, http://uranus.wat.edu.pl:8808/wiki/index.php/ SENSE (access: 2017.05.05)

[8] PATRON project wiki, http://uranus.wat.edu.pl:8808/wiki/index.php/ PATRON (access: 2017.05.05)

[9] Myo tech spec: https://www.myo.com/techspecs

[10] B. Stern: Inside Myo, adafruit.com (2016), https://learn.adafruit.com/myo-armbandteardown/inside-myo

[11] Myo Bluetooth Low Energy specification file, https://github.com/thalmiclabs/myobluetooth/blob/master/myohw.h

[12] R. Hoffmann, M. Kiedrowicz, J. Stanik, Risk management system as the basic paradigm of the information security management system in an organization, 20th International Conference on Circuits, Systems, Communications and Computers, MATEC Web of Conferences, Cedex A: E D P Sciences, vol. 76, (2016).

[13] M. Kiedrowicz, T. Nowicki, R. Waszkowski, Z. Wesolowski, and K. Worwa, Method for assessing software reliability of the document management system using the RFID technology, 20th International Conference on Circuits, Systems, Communications and Computers, MATEC Web of Conferences, Cedex A: E D P Sciences, vol. 76, (2016).

[14] M. Kiedrowicz, Location with the use of the RFID and GPS technologies - opportunities and threats, GIS ODYSSEY 2016, pp. 122-128, (2016).

[15] M. Kiedrowicz, Objects identification in the informations models used by information systems, GIS ODYSSEY 2016, pp. 129-136, (2016).

[16] M. Kiedrowicz, T. Nowicki, R. Waszkowski, Business process data flow between automated and human tasks, 3rd International Conference on Social Science (ICSS 2016) December 9–11 2016, pp. 471-477, (2016).

[17] M. Chmielewski, M. Nowotarski, Sensor-based mobile system supporting Parkinson disease clinical tests utilising biomedical and RFID technologies, 21st International Conference on Circuits, Systems, Communications and Computers (CSCC 2017), Agia Pelagia Beach, Crete Island, Greece, July 14-17, 2017

WSEAS Transactions on Biology and Biomedicine, ISSN / E-ISSN: 1109-9518 / 2224-2902, Volume 14, 2017, Art. #19, pp. 134-144

Copyright © 2017 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution License 4.0

Bulletin Board


The editorial board is accepting papers.

WSEAS Main Site