Plenary Lecture

Present Situation and Future Trends of Omics-Based Medicine and Systems Pathology

Professor Hiroshi Tanaka
School of Biomedical Sciences
Tokyo Medical and Dental University
JAPAN
E-mail: tanaka@cim.tmd.ac.jp

Abstract: A new perspective for personalized and predictive care which clinical omics and bioinformatics cooperatively open will be presented, with emphasis on promising possibilities which “omics-based personalized care” is thought to bring about. In doing so, we take it into consideration that, along the rapid progress of the omics and bioinformatics, the contents of “genome/omics-based personalized care” have evolved, mainly through three generations. The first generation is personalized care based on (1) the polymorphism of the “germline” genome sequences, such as personalized medication depending on the individual genetic differences concerning the pharmacodynamics/phamarcokinetics or estimation of genotype relative risk for individual’s disease occurrence, the second generation is that based on (2) the information pattern of vast amount of omics data of diseased “somatic” cell, which brings about detailed classification, early diagnosis and prognosis of the disease, and the third generation is that based on (3) the system level understanding of complex diseases which enables wholistic comprehension of the mechanism of diseases, with special reference to disease pathway.

Brief Biography of the Speaker:
Date of birth: September 15, 1949
Home address: 4-29-14 Hakusan, Bunkyo-ku, Tokyo, Japan 112-0001
Affiliation: Professor, Department of computational biology, School of Biomedical sciences, Department of bioinformatics
Medical Research Institute
Dean, Biomedical science PhD program
Director, Information Center for Medical Sciences
Tokyo Medical and Dental University
Phone: +81-3-5808-5839
E-mail: tanaka@cim.tmd.ac.jp
Education
1974: Graduated from Department of Mathematical Engineering Faculty of Engineering, University of Tokyo
1976: Received Master of Engineering from the Graduate School of Engineering, University of Tokyo
1981: Received Doctor of Medical Science from Graduate School of Medicine, University of Tokyo
1983: Received Ph.D. from Graduate School of Engineering, University of Tokyo
Academic career
1982-1987: Assistant Professor at the Institute for Medical Electronics, School of Medicine, University of Tokyo
1982-1984: Visiting Scientist, at Uppsala University and Linkoping University, Sweden
1987-1991: Associate Professor, Hamamatsu University School of Medicine
1990: Visiting scientist in MIT Laboratory of Computer Science
1991-2003: Professor of bioinformatics, Medical Research Institute, Tokyo Medical and Dental University
1995-now: Director of Information center for Medicine, Tokyo Medical and Dental University
2003-now: Professor of computational biology, School of Biomedical Sciences, Tokyo Medical and Dental University